Monday, October 29, 2012

Bombing near market kills 3 people in Iraq

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Thursday, October 25, 2012

Computers and Technology Data Disaster Recovery Solutions That

Data Disaster Recovery Solutions That Will Save Your Business

Organizations around the country have learned to take the time to come up with detailed data disaster recovery solutions in order to keep their internal data safe from being lost or stolen. This article will explain some of the most effective data recovery solutions to keep your business from suffering a devastating loss. Data Disaster happens when a business software or storage loses all or vital information due to computer failure, user error, or many times a natural disaster can cause significant damage especially when it directly contacts your server.

A few solutions to make sure these situations are avoided starts with having backups for all your existing files created and saved in more than one place. Choosing to utilize offsite backup to transmit and safely secure important data is a way to stave off future complications. Online data backup is a way to restore information quick and easy with the guaranteed security that a new business is looking for. When searching for backups for your business there are a few key components to pay close attention too. With an offsite solution you will have the luxury during a fire or natural disaster to still be able to retrieve any loss of data if your office is destroyed or damaged.

One feature with an offsite disaster solution is that replication of your data will not need any restoration. Restoration can be time consuming so eliminating this will benefit your company as you attempt to get business back to normal. Outsourcing with a specialized data backup company can be very smart for new businesses who want to be more confident in their data security. Losing data can cause significant damage to a companies financially as well as productivity. This all depends on how long you are down after a disaster occurs. With the correct solution you should have no problems getting your business back up and running in no time.

It is essential that you have backup when coming up with a disaster recovery solution because without your going to shell out a lot of money to restore lost files. For a small business this can become extremely expensive and in many cases sending you down the road to bankruptcy. Having security on your data is vital especially as the use of computers grow and the demand businesses ask our technology to accommodate too. As business expands exploring methods to get rid of data loss will heighten as well. Choosing offsite or onsite backup means you are going in the right direction in securing your business. Over time using both solutions as a way to keep your company safe will be money well spent. Having key records saved to an offsite backup server as well as the countless onsite options is the best way to keep things under your control. There is never any time to take chances on vital information in business. Taking care of your data will lead to greater productivity and potential more money gained.

This entry was tagged Data Disaster, disaster recovery solutions, offsite, offsite backup, time. Bookmark the permalink.

Source: http://www.professorratzhole.com/data-disaster-recovery-solutions-that-will-save-your-business.html

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Source: http://funabe.posterous.com/computers-and-technology-data-disaster-recove

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Source: http://climax-saltcellar.blogspot.com/2012/10/computers-and-technology-data-disaster.html

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Source: http://osmund-knock.blogspot.com/2012/10/computers-and-technology-data-disaster.html

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Chewing betel quid exposes half a billion people to direct carcinogens

Chewing betel quid exposes half a billion people to direct carcinogens [ Back to EurekAlert! ] Public release date: 24-Oct-2012
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Chewing betel quid the fourth most popular psychoactive substance in the world after tobacco, alcohol and caffeine exposes its 600 million users to substances that act as direct carcinogens in the mouth, scientists are reporting in a new study. It appears in ACS' journal Chemical Research in Toxicology.

Mu-Rong Chao and Chiung-Wen Hu explain that betel quid (BQ) consists of nuts from the arcea tree, sometimes combined with spices, such as cardamom or saffron, and other ingredients. Available in commercial forms, BQ is popular among people in China, India and other Asian countries, and people of Asian heritage living in the U.S. and other countries. Scientists have known for decades that chewing BQ can lead to oral cancer, and showed recently that the substances in BQ could be changed into carcinogens in the body. The authors of this study explored whether there were any substances in the arcea nut that can cause cancer directly, without any need for the body to change or "activate" them.

They discovered that compounds in the arcea nut can "alkylate" the genetic material DNA, causing changes that increase the risk of cancer, and they are present in betel quid in amounts high enough to do so. "Our study showed that these alkylating agents are present at levels sufficient to cause DNA damage and could potentially have adverse implications to human health, particularly in the case of the development of oral cancer for BQ chewers," they say.

###

The authors acknowledge funding from the National Science Council, Taiwan.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Chewing betel quid exposes half a billion people to direct carcinogens [ Back to EurekAlert! ] Public release date: 24-Oct-2012
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Chewing betel quid the fourth most popular psychoactive substance in the world after tobacco, alcohol and caffeine exposes its 600 million users to substances that act as direct carcinogens in the mouth, scientists are reporting in a new study. It appears in ACS' journal Chemical Research in Toxicology.

Mu-Rong Chao and Chiung-Wen Hu explain that betel quid (BQ) consists of nuts from the arcea tree, sometimes combined with spices, such as cardamom or saffron, and other ingredients. Available in commercial forms, BQ is popular among people in China, India and other Asian countries, and people of Asian heritage living in the U.S. and other countries. Scientists have known for decades that chewing BQ can lead to oral cancer, and showed recently that the substances in BQ could be changed into carcinogens in the body. The authors of this study explored whether there were any substances in the arcea nut that can cause cancer directly, without any need for the body to change or "activate" them.

They discovered that compounds in the arcea nut can "alkylate" the genetic material DNA, causing changes that increase the risk of cancer, and they are present in betel quid in amounts high enough to do so. "Our study showed that these alkylating agents are present at levels sufficient to cause DNA damage and could potentially have adverse implications to human health, particularly in the case of the development of oral cancer for BQ chewers," they say.

###

The authors acknowledge funding from the National Science Council, Taiwan.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-10/acs-cbq102412.php

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OEM Business Development Sales Manager - West Coast Region ...

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OEM Business Development Sales Manager - West Coast Region

Job ID: 11222204
Position Title: OEM Business Development Sales Manager - West Coast Region
Location(s): Los Angeles, California, 90001, United States ?
Posted: October 24, 2012
Company Name: Allstate
Entry Level: No

Research Tools:

Location MapSee Location on Map Learn MoreLearn More About Location

Develop national sales strategies and sales pipeline to grow the Auto wholesale and Allstate Products through contracting of new partners. Responsible for achieving operating plan targets for new sales revenue for the division.


National VP Sales ? Auto Wholesale

Independently identify, prospect, negotiate and close agreements with new partners.

? Research and identify key prospect decision makers and present appropriate product offerings

? Manage RFP process with Sales Coordinator

? Engage key stakeholders into pricing and deal strategy, product/channel offers and test through rollout plans

? Fully meet and/or exceed key sales targets: Annual revenue goals, contract conversion, sales process milestones, product/channel penetration

? Develop and execute strong partner transition plans from Sales to Relationship Management team

? Strong business knowledge within the OEM industry

? Ability to develop effective internal relationships across business functions

? Overnight travel

? Maintain industry relationships

Requisition #: CAL00101


Source: http://jobs.insurancesalesweb.com/c/job.cfm?site_id=1636&jb=11222204

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Wednesday, October 24, 2012

Viscorra's random free art of CHANCE

Make sure you:
- State why you're leaving.
- Make some recommendations on how to improve these things.
- Tell people how to get in touch of you

We're sorry that you're leaving RolePlayGateway, but remember that we do care a lot about you and the roleplaying community in general. We will take your feedback to heart and will do our best to make sure things improve!

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/cc5JJvT0aII/viewtopic.php

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BBC ripped for handing of sex abuse scandal

Peter Macdiarmid / Getty Images

BBC Director General George Entwistle leaves Parliament on Tuesday after giving evidence to a select committee where he denied charges of a cover-up.

By Peter Jeary, NBC News

The predatory pedophilia of a former British radio and TV celebrity has shaken the BBC to its foundations, as the broadcaster struggles to reconcile itself to charges of mismanagement and allowing an "unacceptable culture" of sexual abuse to go unchecked for decades.

Jimmy Savile, who died in October 2011 two days before his 85th birthday, rose to fame in the 1960s as a dance-hall promoter and later BBC radio disc-jockey. In the 1970s, 80s and 90s, he was a regular fixture of the BBC TV schedules, where his popular, family-oriented shows attracted top ratings. He was honored by the queen, networked with politicians and celebrities and was feted for his charity fundraising and good works.

But in the months since Savile's death, a catalog of accusations has emerged, stretching from 1959 to 2006, in what London's Metropolitan Police described as "abuse on an unprecedented scale."

It has also come out that Savile's sexual exploitation of children may have been known to some people at the time, including former colleagues and managers at the BBC, who failed to report or act upon the rumors and accusations. What's more, it has been revealed that in late 2011, the BBC axed an investigative news item into Savile's pedophilia at the same time that it was planning a Christmas tribute program to him.

UK in turmoil after multiple claims kids' entertainer molested children for years

The head of the BBC denied on Tuesday helping to cover up the allegations but accepted that it had been damaged by the crisis.

In a BBC TV documentary broadcast Monday night, Panorama investigated the original news item, which was to have aired on BBC TV's Newsnight program until it was shelved by the Newsnight editor.

By accessing the original Newsnight video and interviews, Panorama drew a portrait of Savile as a shrewd, calculating and devious predator who preyed on vulnerable young people. Among the accusers were some victims who said Savile had sexually abused them in his BBC dressing room after he recorded his TV shows.

Panorama also looked into the circumstances that led to the Newsnight item being dropped.

Suggestions that it was dropped as part of a BBC cover-up were refuted in a blog by the program's editor, Peter Rippon,?who wrote, "I was told in the strongest terms that I must be guided by editorial considerations only and that I must not let any wider considerations about the BBC affect my judgement."

However, on Monday Rippon "stepped aside" from his post as the BBC issued a correction?to his blog, in which it became clear that Rippon had made factual errors about what the BBC had known. In particular, the correction clarified that there were "some allegations of abusive conduct on BBC premises."

'Broader cultural problem'
BBC director-general George Entwistle was quizzed on Tuesday about all of this by a parliamentary select committee?into the BBC's handling of the affair.

Although he denied the BBC was facing "its worst crisis in 50 years", Entwistle said Savile's alleged behavior had been possible only because of a "broader cultural problem" at the BBC.

When pressed by parliamentarians for detail, Entwistle told them, "We are looking at between five and 10 serious allegations relating to activities over the whole period in question, the Savile period." He added the allegations included claims of sexual harassment made against people still working at the BBC, but could not say how many.

The director-general's grilling created an impression of BBC management out of touch with the broadcaster's day-to-day running.

Instead of evidence of management interference in editorial matters, committee members described themselves as "astonished" at the "lack of curiosity" exhibited by senior management into rumors and "water-cooler" revelations.

The BBC has announced two independent reviews into the Savile affair: one looking at how the abuse he is accused of could have been allowed to happen, and the other looking into the circumstances of the shelved Newsnight item.

Meanwhile, the police enquiry into Savile's activities has developed into a criminal investigation which has yet to establish the full extent of his crimes. Police are following more than 400 lines of enquiry involving more than 200 potential victims.

More world stories from NBC News:

Follow World News from NBCNews.com on Twitter and Facebook

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Source: http://worldnews.nbcnews.com/_news/2012/10/23/14644264-bbc-ripped-for-handing-of-sex-abuse-scandal-tied-to-former-host?lite

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Tuesday, October 23, 2012

The Baton Rouge Halloween Parade is on THIS SATURDAY! Grab your ghouls and gobli...

Sorry, Readability was unable to parse this page for content.

Source: http://www.facebook.com/photo.php?fbid=10151314742971929&set=a.129011961928.119783.83350716928&type=1

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Exxon Mobil Receives Green Cross Safety Award

The National Safety Council has announced that Exxon Mobil Corporation is the recipient of its 2013 Green Cross for Safety medal. The company was awarded the prize "for its comprehensive commitment to safety excellence," the council stated. Here are the details.

* The Green Cross for Safety medal, established in 2000, is awarded annually to organizations who demonstrate a commitment to "improving safety and health in the workplace and beyond," the National Safety Council explained.

* According to the council, Exxon Mobil -- the largest publicly traded international oil and gas company -- has accomplished safety, security, health and environmental performance through clearly defined policies and practices.

* In spite of the award, Exxon Mobil acknowledged in its 2011 Corporate Citizen Report, released in June, that there were some undesirable outcomes for the year found in its performance data.

* Once of the undesirable performance trends indicated in the report was 484 spills involving oil, chemical and drilling fluid not from marine vessels. These incidences were a dramatic increase from the 210 spills Exxon Mobil reported in 2010.

* The company also reported that it had nine fatalities of contractors in 2011, while there were only three in 2010. The fatal accident and lost-time incident rate for the total workforce increased last year over 2010 levels.

* "This year, some of the trends in our safety and environmental performance did not meet our expectations and we are taking action to address them," stated Rex W. Tillerson, Exxon Mobil Chairman and CEO in the 2011 Corporate Citizenship Report. "We will not stop working to achieve our goal of driving accidents and incidents with a real impact to zero."

* Exxon Mobil currently has operations on six continents, the company reported, stating that it strives to become part of local communities and economies in addition to supplying energy.

* The National Safety Council plans to honor Exxon Mobil for its achievement at an April 2013 event in Houston, Texas.

Source: http://news.yahoo.com/exxon-mobil-receives-green-cross-safety-award-204700566.html

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MCGRUDER DEPARTS WDAF-FOX4 ON EVE OF SWEEPS ...

JohnLandsberg
October 22nd, 2012

Sources have told Bottom Line Communications that Bryan McGruder, Vice President of News at WDAF-Fox 4 for nearly 10 years, is no longer with the station.

No reason was given for his sudden exit.

What is particularly surprising with the move is that the all-important November TV sweeps is starting this Friday.? Not having a someone in that key position could severely impact the Fox station?s results.

McGruder, 52, ?joined the station in December 2002 after serving about two years as the VP of News at Fox affiliate WHBQ-TV in Memphis.? He also spent a year as news director at?WJCL/WTGS TV in Savannah, GA, and 10 years as an anchor/reporter/producer and executive producer at WHNT-TV in Huntsville, AL.

Following graduation from the University of Missouri in 1982 McGruder spent two years at WTOK-TV in Meridian, MS, ?as a reporter for four years?and then moved to to WAPT in Jackson, MS, for two years before moving on to WHNT.

McGruder served from 2006-2011 on the Board of Governors of the National Association of the Arts & Sciences as a VP-Trustee.

Source: http://www.bottomlinecom.com/mcgruder-departs-wdaf-fox4-on-eve-of-sweeps/

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Monday, October 22, 2012

The endogenous definition of money (business accounting view ...

What?s money? According to Hyman Minsky (emphasis added):

?Modern capitalist economies are intensely financial. Money in these economies is endogenously determined as activity and asset holdings are financed and commitments of prior contracts are fulfilled. In truth, every economic unit can create money ? this property is not restricted to banks. The main problem a ?money creator? faces is getting his money accepted?

Does everybody agree? No. According to a very recent ECB study about international liquidity (emphasis added):

The concept of monetary liquidity attempts to capture the ability of economic agents to settle their transactions using money, an asset the agents cannot create themselves. Money is typically seen as the asset which, first, can be transformed into consumption without incurring transaction costs, and second, has an exchange value that is not subject to uncertainty in nominal terms, rendering it the most liquid asset in the economy. Strictly speaking, these characteristics apply only to currency. The question of which other assets can be defined as money depends on the degree of substitutability between currency and these other assets. In practice, the definition of money in an economy generally includes those other assets which can be easily converted into currency: short-term bank deposits are an obvious example.

Who?s right? According to business accounting: Minsky.

Main stream economists define money as a combination of a

* unit of account (which by the way existed long before currency)
* means of payment
* store of value

Which means that the ?receivables? on the balance sheets of companies are money, too.

An example: company A buys stuff from company B and promises to pay within six weeks (which happens all the time and provides the liquidity which make markets work). According to the law, according to business accounting and, last but not least, according to the the tax man this is a legal and binding transaction ? even if the debt is not settled you will have to pay taxes and you have to add it to your turnover data. The unit of the ?receivable? (might be Euro 15,79 but that?s a unit, too) enters the balance sheet and the profit and loss account (as it?s a store of value) and was used as a means of exchange. It?s money. Temporary money, yes, but that?s money too. So, Minsky is right, according to business economics ? and the fact that transactions create payables (the debt which serves as the collateral of the receivable) means that transactions lead to money creation. Minsky is right and the ECB isn?t, which makes these ECB economists misunderstand the deeply financial nature of our economy. Money is an social act, not a good.

And this is not a measly amount of money. I?ve checked the balance sheets and profit and loss accounts of five large Dutch companies, ?receivables? alone are 90 billions of Euro?s and sometimes over 20% of total sales.

P.S. ? the idea that using money does not involve transaction costs is bonkers. Last time I checked interest on my mortgage was still 4,6%, money which I have to pay as I once needed money to use money to buy a house. And see also this recent ECB study, which estimates that making retail transactions alone cost us about 1% of GDP, not counting transport costs to and from the shops (those are market and not paying transactions costs).
?

Source: http://rwer.wordpress.com/2012/10/21/the-endogenous-definition-of-money-business-accounting-view/

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NBC/WSJ Poll: Views Improving For Romney, Economy

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How a fish 'broke' a law of physics

ScienceDaily (Oct. 21, 2012) ? Silvery fish such as herring, sardine and sprat are breaking a basic law of physics, according to new research from the University of Bristol published October 21 in Nature Photonics.

Reflective surfaces polarize light, a phenomenon that fishermen or photographers overcome by using polarizing sunglasses or polarizing filters to cut our reflective glare. However, PhD student Tom Jordan and his supervisors Professor Julian Partridge and Dr Nicholas Roberts in Bristol's School of Biological Sciences found that these silvery fish have overcome this basic law of reflection -- an adaptation that may help them evade predators.

Previously, it was thought that the fish's skin -- which contains "multilayer" arrangements of reflective guanine crystals -- would fully polarize light when reflected. As the light becomes polarized, there should be a drop in reflectivity.

The Bristol researchers found that the skin of sardines and herring contain not one but two types of guanine crystal -- each with different optical properties. By mixing these two types, the fish's skin doesn't polarize the reflected light and maintains its high reflectivity.

Dr Roberts said: "We believe these species of fish have evolved this particular multilayer structure to help conceal them from predators, such as dolphin and tuna. These fish have found a way to maximize their reflectivity over all angles they are viewed from. This helps the fish best match the light environment of the open ocean, making them less likely to be seen."

As a result of this ability, the skin of silvery fish could hold the key to better optical devices. Tom Jordan said: "Many modern day optical devices such as LED lights and low loss optical fibres use these non-polarizing types of reflectors to improve efficiency. However, these human-made reflectors currently require the use of materials with specific optical properties that are not always ideal. The mechanism that has evolved in fish overcomes this current design limitation and provides a new way to manufacture these non-polarizing reflectors."

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/7_bS-SJCv4w/121021133911.htm

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Sunday, October 21, 2012

Natural process activating brain's immune cells could point way to repairing damaged brain tissue

ScienceDaily (Oct. 21, 2012) ? The brain's key "breeder" cells, it turns out, do more than that. They secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding adds a new dimension to our understanding of how resident stem cells and stem cell transplants may improve brain function.

Many researchers believe that these cells may be able to regenerate damaged brain tissue by integrating into circuits that have been eroded by neurodegenerative disease or destroyed by injury. But new findings by scientists at the Stanford University School of Medicine suggest that another process, which has not been fully appreciated, could be a part of the equation as well. The findings appear in a study that will be published online Oct. 21 in Nature Neuroscience.

"Transplanting neural stem cells into experimental animals' brains shows signs of being able to speed recovery from stroke and possibly neurodegenerative disease as well," said Tony Wyss-Coray, PhD, professor of neurology and neurological sciences in the medical school and senior research scientist at the Veterans Affairs Palo Alto Health Care System. "Why this technique works is far from clear, though, because actually neural stem cells don't engraft well."

Neural stem cells can endure essentially unchanged for decades in two places in the mammalian brain, replicating just enough to meet the routine needs of those regions. In most parts of the brain, they aren't found at all.

While of critical importance to maintaining healthy brain function, true neural stem cells are rare. Far more common are their immediate progeny, which are called neural progenitor cells, or NPCs. These robust, rapidly dividing cells are poised to travel down a committed path of differentiation to yield new brain cells of several different types including neurons.

It's known that treating humans with radiation or drugs that prevent NPC replication causes memory deficits ("chemo brain") and, in children, IQ losses of up to 20 points. Conversely, studies are being initiated to see whether infusing neural stem cells into brains affected by Alzheimer's disease can enhance patients' memory function.

One category of brain cells, microglia, descends not from neural stem cells but from an immune lineage and retains several features of immune cells. "Microglia are the brain's own resident immune cells," Wyss-Coray said. Unlike most other mature brain cells, microglia can proliferate throughout adulthood, especially in response to brain injury. They can, moreover, migrate toward injury sites, secrete various "chemical signaling" substances, and gobble up bits of debris, microbial invaders or entire dead or dying neurons.

Microglia normally are distributed throughout the brain -- rather small, quiescent cells sprouting long, skinny projections that meekly but efficiently survey large areas that, taken together, cover the entire brain. But if this surveillance reveals signs of a disturbance, such as injury or infection, the microglia whirl into action. They begin proliferating and their puny bodies puff up, metamorphosing from mild-mannered Clark Kent-like reporters to buffed Supermen who fly to the scene of trouble, where they secrete substances that can throttle bad actors or call in reinforcements. Within these activated cells, internal garbage disposals called lysosomes form in large numbers and start whirring, ready to make mincemeat out of pathogens or cellular debris.

In addition to their part patrol-officer, part cleanup-crew status, microglia can also secrete substances that help neurons thrive. They also contribute to the ongoing pruning of unneeded connections between neurons that occurs throughout our lives.

But like immune cells elsewhere, said Wyss-Coray, microglia can be a force for evil if they engage in too much or inappropriate activity. They might, for instance, start to remove healthy cells (as occurs in Parkinson's) or stop cleaning up garbage strewn about the brain (for example, Alzheimer's plaque).

In a series of experiments, Wyss-Coray and his colleagues have shown that NPCs secrete substances that activate microglia. First, the researchers observed that microglia were uncharacteristically abundant and activated in the two regions in the mammalian brain where NPCs reside and new neurons are formed. Wondering whether the NPCs might be causing this increased microglial activity, the investigators incubated mouse microglia in a culture medium in which NPCs had previously been steeped. Two days later, they saw that the microglia had multiplied more, expressed different amounts of various signal molecules and featured more lysosomes. "The microglia were ready for action," said Wyss-Coray.

So they injected NPCs into an area of mice's brains where these cells are normally not found. In the same area in the opposing brain hemisphere, they injected a control solution. Again they found significant differences in microglial proliferation and activity, and more microglia in the NPC-injected side had assumed a "Superman" as opposed to a "Clark Kent" body shape. When they repeated this experiment using only the NPCs' "discarded bath water" rather than NPCs themselves, they got similar results.

Clearly NPCs were secreting something, or some things, that were spurring microglia to action.

Using sophisticated lab techniques, the team monitored purified NPCs plus several other cell types found in the brain and assessed nearly 60 different substances known to have powerful cell-to-cell signaling properties. Several such substances, it turned out, were secreted in much larger amounts by NPCs than by the other cell types: most notably, vascular endothelial growth factor, or VEGF -- a well-known molecule produced by many cell types throughout the body. VEGF stimulates the formation of blood vessels and exerts a beneficial effect on neurons. Conversely, drugs that block VEGF (such as Avastin) are frequently used to combat cancer because tumors require an immense blood supply in order to grow quickly.

VEGF is also known to boost microglial proliferation. Because it is produced in such volumes by NPCs, Wyss-Coray's team wanted to see if VEGF alone could mimic any of the changes wrought by NPCs or their culture-medium-borne detritus. So they injected VEGF into mice's right brain hemisphere, and saline solution into the left -- again with the same outcomes. Taking the opposite tack, the team injected NPC-saturated medium devoid of the cells, as they had done earlier. But this time they first used various laboratory techniques to deplete the fluid of the VEGF secreted by its former inhabitants. Doing this almost completely reversed its microglia-activating effects.

"All of this strongly suggests that VEGF produced by NPCs is playing a strong role in influencing microglial behavior," said Wyss-Coray. "This is important, because in all neurodegenerative diseases we know of we see microglia out of control." The new finding may open the door to reprogramming misbehaving microglia to play better with other cells.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/g0wPwQxtoGc/121021133924.htm

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Pope creates first Native American saint

Lucas Jackson / Reuters

A statue of St. Kateri Tekakwitha in Auriesville, New York, seen on Friday.

By Claudio Lavanga, NBC News

VATICAN CITY - She was known as Lily of the Mohawks, or the Pocahontas of the Catholic Church. But on ?Sunday, Kateri Tekakwitha went down in history as the first Native American saint.

Born more than 300 years ago in the Mohawks village of Ossernion - today Ausierville, forty miles from Albany NY - she was one of seven people canonized by Pope Benedict XVI Sunday in an open-air ceremony held in Saint Peter?s Square.?

One of the remaining six was also American: Mother Marianne Cope, a 19th century Franciscan nun who cared for leprosy patients in Hawaii.

Kateri had a short life ? she died at 24 ? and yet, as for most saints, her devotion to Christianity, sacrifices and ?heroic virtue? were so inspirational that her legacy survived for generations.

Alessandra Tarantino / AP

Pope Benedict XVI kisses the altar as he celebrates a canonization ceremony, in St. Peter's Square, at the Vatican, Sunday.

Her mother was a Christian Algonquin woman who was captured during a raid and given as wife to a Mohawks tribal member. She was born in the middle of the 17th century, a time of infighting between rival American tribes, deadly diseases and colonization. And a time when French Jesuit priests preached in the area, trying to convert locals to Christianity.

PhotoBlog: inaugurates 'Year of Faith' amid concerns over rising secularism

Kateri was only four years old when a smallpox epidemic spread among the Mohawks tribe. Her parents and younger brother were killed and although she survived she was left with permanent scars on her face and an impaired vision. The Jesuit priests were held accountable for having brought the disease, and three of them were slaughtered.

Tiziana Fabi / AFP - Getty Images

A faithful wearing Indian headress attends a special mass to name seven new saints in St Peter's square at Vatican on Sunday.

And yet, at the age of 20, Kateri swapped the Totem for the Crucifix.

She converted to Catholicism after living close to French Jesuit priests, something her family and village saw as a betrayal for siding up with colonizers. She soon became a pariah in her own tribe after refusing to marry a Mohawk man, and was forced to leave the village to practice freely her new faith. She walked hundreds of miles to Quebec, Canada, to join a community of Christian women, and took a vow of lifetime chastity.

Soon her devotion led to self-inflicted painful penances. She is believed to have walked barefoot in show, for whipping herself bloody with reeds, praying hours in an unheated chapel on her bare knees on a cold stone floor or for sleeping on a bed of thorns.

In the end, the punishing penances are believed to have contributed to the weakening of her health, until her premature death at 24 years old. And it was immediately after her death, the legend goes, that it became clear she would be on her way to sainthood. Her smallpox scars, witnesses claimed, miraculously disappeared minutes after her death.

Although the petition for her canonization was filed in 1884, she was only blessed ? the first step to become a saint ? by Pope John Paul II in 1980.

Video shows an anti-austerity protester jumping the railing at the observation deck atop St. Peter's Basilica at the Vatican to set up camp with a sign on the iconic Italian dome. NBC's Michelle Kosinski reports.

The miracle that sealed her sainthood came in 2006, when Jake Finkbonner, then a 5-year old boy from Ferndale, WA, miraculously recovered from a flash-eating bacteria, allegedly through Kateri?s intercession. Jake contracted Necrotizing fasciitis, a potentially deadly infection, after cutting his lip on a baseball field. In a matter of days, his condition became so critical his parents gave him his last rites and discussed donating his organs.

When medical help seemed hopeless, his father Donny, a Catholic member of the native American Lummi tribe, turned to Kateri, already an icon in the local catholic community and the subject of many stories he heard as a child. His congregation prayed Kateri and his mother even placed a small relic, a small piece of Tekakwitha?s wrist bone, on his body. ?Soon after, Jake recovered.

On his website, Jake also remembers the role played by doctors: ?Please don't confuse the issue which is that my survival is a miracle?, he writes.? ?We thank the doctors at Children's Hospital for all that they did to save my life.? I wouldn't be here without them?.

Pope Benedict's XVI former butler took the stand in a Vatican courtroom and admitted to stealing private documents from the papal apartment, but ?Paulo Gabriele said he didn't feel guilty of aggravated theft.? He also said he feels guilty of betraying the pontiff's trust.? NBC's Claudio Lavanga reports.??

The canonization of Kateri has been welcomed with mixed feelings in the 2.5 million-strong Native American community. While most of the 680,000 catholic Native Americans are thrilled to finally have their own saint and icon, others still resent the role of Catholicism during the colonial era and the way it affected the indigenous traditions, culture and customs.?

Some traveled to Rome to see the ceremony.?Dressed in a traditional Indian Squaw brown dress and braided hair, Valery Moran had come from Saskatchewan, Canada, to support her hero. ?I am honored to witness the canonization of our first aboriginal saint?, she told NBC News.

"She is my role model, I named my baby after her. My baby is called Kateri."

Bill Volker, a falconer and sole representative of the Comanche Nation, had mixed feelings about the canonization. "It?s bittersweet, but I am delighted. It?s the right direction after all these years,? he told NBC News in St. Peter?s Square. ?Our relationship with the all churches have not always been the best in the Americas, but I think this heralds a new day for us?.?

The Vatican's complicated saint-making procedure requires that the Vatican certify a "miracle" was performed through the intercession of the candidate ? a medically inexplicable cure that can be directly linked to the prayers offered by the faithful. One miracle is needed for beatification, a second for canonization.?

The five other new saints are: Jacques Berthieu, a 19th century French Jesuit who was killed by rebels in Madagascar, where he had worked as a missionary; Giovanni Battista Piamarta, an Italian who founded a religious order in 1900 and established a Catholic printing and publishing house in his native Brescia; Carmen Salles Y Barangueras, a Spanish nun who founded a religious order to educate children in 1892; and Anna Schaeffer, a 19th century German lay woman who became a model for the sick and suffering after she fell into a boiler and badly burned her legs. The wounds never healed, causing her constant pain.

The Associated Press contributed to this report.

More world stories from NBC News:

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Source: http://worldnews.nbcnews.com/_news/2012/10/21/14591532-kateri-tekakwitha-named-first-native-american-saint-in-vatican-ceremony

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Pa. pavilion collapses; 10-12 have minor injuries

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Anna Nicole Smith lawyer Howard Stern back on the hook for conspiracy charges

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Saturday, October 20, 2012

Breast Cancer Risk Predicted by Blood Hormone Levels ...

Researchers have found that blood hormone tests can predict a woman?s risk of postmenopausal breast cancer for up to 20 years.

The study used data from the Nurses Health Study and looked at 796 patients with postmenopausal breast cancer who had not received hormone therapy, and each was matched with two controls who were not diagnosed with breast cancer. Blood tests had been conducted on these women during the periods 1989 to 1990 and 2000 to 2002. The researchers found a single hormone level that was associated with breast cancer.

?We found that a single hormone level was associated with breast cancer risk for at least 16 to 20 years among postmenopausal women not using postmenopausal hormones,? said Dr. Xuehong Zhang, lead author of the study and instructor at Brigham and Women?s Hospital at Harvard Medical School. ?We, and others, are now evaluating if the addition of hormone levels to current risk prediction models can substantially improve our ability to identify high-risk women who would benefit from enhanced screening or chemoprevention ? if so, the current data suggest that hormone levels would not need to be measured in the clinic more than once every 10, or possibly 20, years.?

Zhang and colleagues also found that women with hormone levels in the highest 25% for estradiol, testosterone, and DHEAS (Dehydroepiandrosterone Sulfate) had a 50% to 107% greater chance of developing breast cancer when compared to the lowest 25%. The researchers stated that, in general, increased hormone levels except for DHEAS ?tracked closely? with an increased risk for receptor-positive breast cancer, and were associated with recurrent or fatal breast cancer.

The study is to be presented at the 11th Annual American Association for Cancer Research (AACR) International Conference on Frontiers in Cancer Prevention Research.

Source: http://www.webpronews.com/breast-cancer-risk-predicted-by-blood-hormone-levels-2012-10

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Markets Weekahead: Blue chip earnings to dominate

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Friday, October 19, 2012

Colombia's Santos: Land restitution law undermines rebels

BOGOTA (Reuters) - Colombian President Juan Manuel Santos on Friday defended his signature law that returns land seized by illegal armed groups to peasants after leftist rebels assailed the measure at the start of peace talks.

Negotiations to end five decades of war started out bumpy this week when Ivan Marquez, lead negotiator for the Revolutionary Armed Forces of Colombia, or FARC, called Santos' restitution law a "trap.

"When these gentlemen from the FARC say this law is a lie it's because ... they know full well that this is something that takes away from one of their propaganda banners," Santos said on his radio program.

One of the FARC's main grievances since taking up arms in 1964 has been the unequal distribution of land, which has been concentrated in the hands of a few since the Spanish conquered the region around the 16th century.

Since coming to power in 2010, Santos' government has pushed through reforms such as the restitution of land to displaced peasants. The move was seen as paving the way for peace talks with the rebels.

Over the conflict's long history, millions of Colombia's rural poor have been forced from their homes by FARC rebels and right-wing paramilitary groups who later used the land to fund their fighting forces.

BOON FOR CORPORATIONS?

On Thursday Colombian government and rebel negotiators agreed to meet in Cuba in mid-November to start what are likely to be difficult talks with the top issues being rural development and land.

Marquez railed against the restitution law at a press conference in Norway.

"Land titles as the current government has designed it are a trap," the guerrilla leader said.

He argued that returning land to peasants who lack the means to make it productive would likely encourage them to sell it cheaply to international corporations.

Various peace efforts in Colombia since the 1980s have brought mixed success, with some smaller armed groups demobilizing. But the FARC, Latin America's biggest rebel group, has pressed on, funded in large part by drug trafficking.

The guerrillas were widely seen to have used previous negotiations to rearm and rebuild their ranks. Right-wing elements linked to Colombia's political establishment also were accused of undermining talks.

The FARC, which traces its roots to the peasant self-defense forces of the 1950s that fought against wealthy landowners, wants to change Colombia's economic system, which Santos' government flatly rules out.

Colombian newspapers and analysts, pointing out the discord between the two sides when talks opened this week in Norway, said the road forward would be very long.

Others were less pessimistic.

"It's important not to over-interpret what the FARC said. They needed to use this as a platform for voicing their political agenda rather than showing flexibility for the talks," said Christian Voelkel, Colombia analyst for the International Crisis Group think tank.

(Reporting by Jack Kimball; Editing by Xavier Briand)

Source: http://news.yahoo.com/colombias-santos-land-restitution-law-undermines-rebels-180309315.html

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